Process Development /
Protein Structure Research
In our state-of-art laboratories we are able to perform all needed routine protein analyses throughout all project stages including final product characterization according to all regulatory requirements.
We perform:
- Protein identification
- Peptide mapping
- Amino Acid Composition Analysis
- Protein sequencing (Maldi-ISD; ESI-MS/MS)
- Disulfide linkages analysis
- Analysis of post-translational modifications (such as oxidation, deamidation)
- Glycosylation analysis
- Proteomics
- Cell metabolites analysis
- Process- or product-related impurity’s identification
- Comparability studies of biosimilar
- Release testing
- Protein-Protein, antibody-antigen interaction analysis
- Affinity and binding kinetics determination
State-of-the-art equipment in combination with the up-to-date software enables us to meet highest analytical requirements. Constantly upgradable and improvable instruments:
- ESI-TOF Mass spectrometer MicrOTOF-Q II Bruker, connected with Waters LC system
- Maldi-TOF Mass spectrometer Autoflex Speed Bruker
- Surface Plasmon resonance instrument - Biacore X100
- Perkin Elmer LS55 Luminescence spectrometer