Protein Structure Research

In our state-of-art laboratories we are able to perform all needed routine protein analyses throughout all project stages including final product characterization according to all regulatory requirements.

We perform:

• Protein identification
• Peptide mapping
• Amino Acid Composition Analysis
• Protein sequencing (Maldi-ISD;  ESI-MS/MS)
• Disulfide linkages analysis
• Analysis of post-translational modifications (such as oxidation, deamidation)
• Glycosylation analysis
• Proteomics
• Cell metabolites analysis
• Process- or product-related impurity’s identification
• Comparability studies of biosimilar
• Release testing
• Protein-Protein, antibody-antigen interaction analysis
• Affinity and binding kinetics determination

State-of-the-art equipment in combination with the up-to-date software enables us to meet highest analytical requirements. Constantly upgradable and improvable instruments:

• ESI-TOF Mass spectrometer MicrOTOF-Q II Bruker, connected with Waters LC system
• Maldi-TOF Mass spectrometer Autoflex Speed Bruker
• Surface Plasmon resonance instrument - Biacore X100
• Perkin Elmer LS55 Luminescence spectrometer